{"product_id":"ara-290-copy","title":"ARA-290 Peptide Pen","description":"\u003ch3\u003ePeptide Name\u003c\/h3\u003e\n\u003cp id=\"p-rc_03685d85c1e9ec19-92\"\u003e\u003cb\u003e\u003cspan class=\"citation-164 citation-end-164\"\u003eARA-290 (Cibinetide)\u003csup class=\"superscript\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003c\/b\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003ch3\u003eChemical Name\/Structure\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp id=\"p-rc_03685d85c1e9ec19-93\"\u003e\u003cb\u003eChemical Name:\u003c\/b\u003e \u003cspan class=\"citation-163 citation-end-163\"\u003eL-pyroglutamyl-L-alpha-glutamyl-L-glutaminyl-L-leucyl-L-alpha-glutamyl-L-arginyl-L-alanyl-L-leucyl-L-asparagyl-L-seryl-L-serine\u003csup class=\"superscript\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eMolecular Formula:\u003c\/b\u003e \u003cspan class=\"math-inline\"\u003e$C_{51}H_{84}N_{16}O_{21}$\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp id=\"p-rc_03685d85c1e9ec19-94\"\u003e\u003cb\u003eStructure\/Sequence:\u003c\/b\u003e \u003cspan class=\"citation-162 citation-end-162\"\u003ePyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-OH (also referred to as Pyroglutamate Helix B Surface Peptide)\u003csup class=\"superscript\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCAS Number\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp id=\"p-rc_03685d85c1e9ec19-95\"\u003e\u003cb\u003eCAS Number:\u003c\/b\u003e \u003cspan class=\"citation-161 citation-end-161\"\u003e1208243-50-8\u003csup class=\"superscript\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eResearch Areas of Focus\u003c\/h3\u003e\n\u003cp\u003eResearchers are actively conducting \u003ci\u003ein vitro\u003c\/i\u003e and laboratory studies on ARA-290 to investigate its molecular behavior in the following areas:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp id=\"p-rc_03685d85c1e9ec19-96\"\u003e\u003cb\u003eInnate Repair Receptor (IRR) Activation:\u003c\/b\u003e \u003cspan class=\"citation-160 citation-end-160\"\u003eStudying how the peptide selectively binds to the erythropoietin-CD131 heteroreceptor (IRR) without triggering erythropoiesis (red blood cell production).\u003csup class=\"superscript\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eNeuropathic Pain and Neuroprotection:\u003c\/b\u003e Investigating the peptide's capability to protect and repair damaged small-fiber nerve networks, particularly in metabolic or systemic nerve loss models.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eInhibition of Pro-inflammatory Cytokines:\u003c\/b\u003e Exploring the downstream signaling mechanisms (such as the NF-\u003cspan class=\"math-inline\"\u003e$\\kappa$\u003c\/span\u003eB pathway) that lead to a decrease in the production of destructive tissue inflammatory mediators.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eTissue Salvage and Wound Healing:\u003c\/b\u003e Analyzing the role of ARA-290 in promoting cellular survival, migration, and proliferation under severe metabolic stress or hypoxic (oxygen-deprived) conditions.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eEndothelial Function and Microvasculature Support:\u003c\/b\u003e Assessing how the compound influences capillary blood vessel survival, local blood flow regulation, and the integrity of cellular linings under high-glucose stress.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cblockquote\u003e\n\u003cp\u003e\u003cstrong\u003eRESEARCH-USE NOTICE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis product is supplied by Biolabs for laboratory and research purposes only. It is not intended to diagnose, treat, cure, or prevent any medical condition and should not be used as a substitute for professional medical advice or treatment.\u003c\/p\u003e\n\u003cp\u003eAny information provided is for general research, product identification, storage, and handling purposes only. The purchaser is responsible for using and storing the product appropriately and in accordance with applicable regulations.\u003c\/p\u003e\n\u003c\/blockquote\u003e","brand":"BIOLABS","offers":[{"title":"10","offer_id":50018640724210,"sku":null,"price":1860.0,"currency_code":"ZAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0826\/5410\/1746\/files\/ae8a4173-60b1-4696-8323-783979e1ab70_998fd9d4-b0e8-4132-939f-1f77f53c5ee0.png?v=1788439079","url":"https:\/\/biolabsresearch.co.za\/products\/ara-290-copy","provider":"Biolabs Peptides South Africa","version":"1.0","type":"link"}