{"product_id":"igf-1-lr3-peptide-pen","title":"IGF-1 LR3 Peptide Pen","description":"\u003ch3 data-path-to-node=\"1\"\u003ePeptide Name\u003c\/h3\u003e\n\u003cp\u003ePrefilled Pen\u003c\/p\u003e\n\u003cp data-path-to-node=\"2\" id=\"p-rc_d33f51e5015edb67-30\"\u003e\u003cb data-path-to-node=\"2\" data-index-in-node=\"0\"\u003e\u003cspan class=\"citation-74 citation-end-74\"\u003eIGF-1 LR3 (Long Arginine 3 Insulin-like Growth Factor-1)\u003csup class=\"superscript\" data-turn-source-index=\"1\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003c\/b\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"3\"\u003eChemical Name\/Structure\u003c\/h3\u003e\n\u003cul data-path-to-node=\"4\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"4,0,0\" id=\"p-rc_d33f51e5015edb67-31\"\u003e\u003cb data-path-to-node=\"4,0,0\" data-index-in-node=\"0\"\u003eChemical Name:\u003c\/b\u003e \u003cspan class=\"citation-73 citation-end-73\"\u003eRecombinant Human Insulin-like Growth Factor-1 Long R3\u003csup class=\"superscript\" data-turn-source-index=\"2\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"4,2,0\" id=\"p-rc_d33f51e5015edb67-32\"\u003e\u003cb data-path-to-node=\"4,2,0\" data-index-in-node=\"0\"\u003eStructure\/Sequence:\u003c\/b\u003e \u003cspan class=\"citation-72 citation-end-72\"\u003eA modified 83-amino-acid analog of human IGF-1 featuring a glutamic acid to arginine substitution at position 3 \u003c\/span\u003e\u003cspan class=\"citation-71 citation-end-71\"\u003e and a 13-amino-acid extension peptide at the N-terminus \u003c\/span\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"4,3,0\" id=\"p-rc_d33f51e5015edb67-33\"\u003e\u003cb data-path-to-node=\"4,3,0\" data-index-in-node=\"0\"\u003eAmino Acid Sequence:\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"4,3,0\" id=\"p-rc_d33f51e5015edb67-33\"\u003e\u003cspan class=\"citation-69\"\u003e\u003c\/span\u003e\u003ccode data-path-to-node=\"4,3,0\" data-index-in-node=\"21\"\u003e\u003cspan class=\"citation-69\"\u003eMFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA\u003c\/span\u003e\u003c\/code\u003e\u003cspan class=\"citation-69 citation-end-69\"\u003e\u003csup class=\"superscript\" data-turn-source-index=\"6\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"5\"\u003eCAS Number\u003c\/h3\u003e\n\u003cul data-path-to-node=\"6\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,0,0\"\u003e\u003cb data-path-to-node=\"6,0,0\" data-index-in-node=\"0\"\u003eCAS Number:\u003c\/b\u003e 946870-92-4 (also referenced under 143045-27-6)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"7\"\u003eResearch Areas of Focus\u003c\/h3\u003e\n\u003cp data-path-to-node=\"8\"\u003eResearchers are actively investigating IGF-1 LR3 in laboratory and \u003ci data-path-to-node=\"8\" data-index-in-node=\"67\"\u003ein vitro\u003c\/i\u003e studies to explore its potential in the following areas:\u003c\/p\u003e\n\u003cul data-path-to-node=\"9\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,0,0\" id=\"p-rc_d33f51e5015edb67-34\"\u003e\u003cb data-path-to-node=\"9,0,0\" data-index-in-node=\"0\"\u003eIGFBP Binding Inhibition:\u003c\/b\u003e \u003cspan class=\"citation-68 citation-end-68\"\u003eInvestigating how the structural modifications block binding to insulin-like growth factor-binding proteins (IGFBPs), thereby increasing the concentration of free, biologically active peptide.\u003csup class=\"superscript\" data-turn-source-index=\"7\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,1,0\" id=\"p-rc_d33f51e5015edb67-35\"\u003e\u003cb data-path-to-node=\"9,1,0\" data-index-in-node=\"0\"\u003eCellular Proliferation and Survival:\u003c\/b\u003e \u003cspan class=\"citation-67 citation-end-67\"\u003eAnalyzing downstream signaling pathways (such as PI3K\/Akt and MAPK\/ERK) that regulate cell growth, protein synthesis, and cellular longevity.\u003csup class=\"superscript\" data-turn-source-index=\"8\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,2,0\"\u003e\u003cb data-path-to-node=\"9,2,0\" data-index-in-node=\"0\"\u003eMyogenesis and Muscle Hyperplasia:\u003c\/b\u003e Studying the peptide's role in promoting the proliferation and differentiation of satellite cells into new muscle fibers (hyperplasia).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,3,0\" id=\"p-rc_d33f51e5015edb67-36\"\u003e\u003cb data-path-to-node=\"9,3,0\" data-index-in-node=\"0\"\u003eExtended Pharmacokinetics:\u003c\/b\u003e \u003cspan class=\"citation-66 citation-end-66\"\u003eAssessing the impact of its significantly extended half-life (estimated at 20–30 hours compared to native IGF-1's 12–15 hours) on prolonged receptor activation in cell cultures.\u003csup class=\"superscript\" data-turn-source-index=\"9\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"9,4,0\"\u003e\u003cb data-path-to-node=\"9,4,0\" data-index-in-node=\"0\"\u003eTissue Repair and Wound Healing:\u003c\/b\u003e Evaluating its potential to accelerate protein and DNA synthesis in injured epithelial, connective, and muscle tissues.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cblockquote data-path-to-node=\"11\"\u003e\n\u003cp\u003e\u003cstrong\u003eRESEARCH-USE NOTICE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis product is supplied by Biolabs for laboratory and research purposes only. It is not intended to diagnose, treat, cure, or prevent any medical condition and should not be used as a substitute for professional medical advice or treatment.\u003c\/p\u003e\n\u003cp\u003eAny information provided is for general research, product identification, storage, and handling purposes only. The purchaser is responsible for using and storing the product appropriately and in accordance with applicable regulations.\u003c\/p\u003e\n\u003c\/blockquote\u003e","brand":"BIOLABS","offers":[{"title":"1","offer_id":49835261788402,"sku":null,"price":3250.0,"currency_code":"ZAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0826\/5410\/1746\/files\/49ce18d2-faa2-48b1-ac45-a6a012ee3364.png?v=1784793474","url":"https:\/\/biolabsresearch.co.za\/products\/igf-1-lr3-peptide-pen","provider":"Biolabs Peptides South Africa","version":"1.0","type":"link"}